1. Silica Gel
Independent lab results show DAI's silica to be the highest quality in the industry with the
lowest amount of trace metals.
Dynamic Adsorbents, Inc. silica gels (product details) are carefully manufactured and quality
assured to provide the ideal laboratory and pilot process chromatographic material. We
control the manufacturing process from raw material to finished product. We carefully control
the physical characteristics of pore size, surface area, particle size and surface chemistry to
ensure reproducible optimized chromatographic behavior for uniform capacity, reproducible
selectivity, improved resolution and excellent performance.
k' - uniform capacity
- reproducible selectivity
RS- improved resolution
N - excellent performance
Reproducible performance is delivered regardless of the technique used, especially when
transferring from one technique to another. Silica gel is an ideal media for column
chromatography for several different reasons. Silica gel has a very strong affinity for water,
which gives it an adsorption capacity of over 40% of its own weight at 100% relative humidity.
It is compatible with most materials except strong alkalis and hydrofluoric acid. Adsorbent
particle size affects how the solvent flows through the column. Smaller particles (higher mesh
values) are used for flash chromatography, larger particles (lower mesh values) are used for
gravity chromatography.
Benefits of Silica
Many silica gel manufacturers provide 40 micron size silica gels. With more than 90% of
silica gel particles in the defined range (32-63 microns), the DAI Flash grade silica provides
18-24% more consistency than any competitive vendor. It is manufactured to satisfy the
rigorous specifications of our demanding customers, separation scientists.
Separation chemists need to remember that not all 40-63 micron silica gels are the same. Try
using this DAI superior high purity, clean particle size product for your separations. The
rewarding results will demonstrate the benefits, reproducible lot to lot consistency in product
yield.
High sample loading
Fewer unwanted reactions during separation
Wide range of chromatographic forms of silica – wide range of surface areas and average
pore diameters
The hydroxyl group in silica is attached to silicon – hydroxyl groups are either free or

2. hydrogen bonded
The silica gels used are amorphous
For What Applications Can Silica Be Used?
“Flash” Chromatography
Column Chromatography
DCC - Dry Column Chromatography
Large Column Chromatography
TLC, HPTLC, HPLC Prep LC.
Pilot - Prep - Process
Analytical QC Methods Development
Advantages of DAI Silica Over Competitors
Highest Quality in the Industry: An independent lab analysis of silica from all major vendors
reveals that the level of unwanted iron, lead and copper contaminants is much less than that
of our competitors – in some cases strikingly so! There is no finer brand of silica gel
commercially available.
Greater Consistency: Many silica gel manufacturers provide 40 micron size silica gels. With
more than 90% of silica gel particles in the defined range (32-63 microns), the DAI Flash
grade silica provides 18-24% more consistency than any competitive vendor.
Particle distribution is kept extremely tight for reproducible results.
Carefully manufactured and quality assured to provide the ideal laboratory and pilot process
chromatographic material
Careful control of the physical characteristics of pore size, surface area, particle size and
surface chemistry ensuring reproducible optimized chromatographic behavior for uniform
capacity, reproducible selectivity, improved resolution and excellent performance.
Full control of the manufacturing process from raw material to finished product.
All silicas can come with MSDS sheets, as well as Certificates of Analysis if requested.
Silica Gel for chromatography