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Pharma Market Dynamics
2Q 2012
• Confidentiality Statement
This presentation is solely for the use of IMS clients. No part of it
may be circulated, quoted or reproduced for distribution outside of
the client organization without prior written approval of IMS Health
• Bangladesh Pharma Market
Bangladesh pharma market: Eskayef is the number
6 company with 4.74% market share
4
18.42
9.52
8.88
5.33 4.93 4.74 4.31 4.12 4.03 3.73
SQUARE INCEPTA BEXIMCO OPSONIN RENATA ESKAYEF A.C.I. ACME ARISTO DRUG
INTL
Share %
Evolution of market share: Top 10 Companies
Recent data indicates good performance of Incepta, Opsonin,
Renata & DI
5
MAT ~ 06/2012 YTD ~ 06/2012 QTR ~ 06/2012
SQUARE 18.42 18.17 17.13
INCEPTA 9.52 9.70 9.78
BEXIMCO 8.88 8.75 8.49
OPSONIN 5.33 5.44 5.47
RENATA 4.93 5.02 5.14
ESKAYEF 4.74 4.74 4.71
A.C.I. 4.31 4.16 4.22
ACME 4.12 4.20 4.07
ARISTO 4.03 4.08 4.07
DRUG INTL 3.73 3.83 3.97
• The Antibiotics Molecules
Antibiotic Market: Top 12 Molecules represents 90%
of the 1700 Crore Taka Market
7
17.63
15.79
11.85
10.96
7.68
6.59 6.55
5.47
2.68
1.98 1.81 1.32
Share %
Clindamycin (39% gr) is the highest growing
molecule, followed by Cefuroxime (19% gr)
8
38.80
19.39 18.12 17.76
15.73
6.65
0.65 0.33
-4.11 -4.32 -5.57
-10.29
Growth %
Top Companies in Antibiotic Market: ESK number 8
Renta 3, ACI 5, Sanofi 9
9
22.29
7.47
6.77 6.43 6.16
5.20 5.11 5.09 4.75
3.47
SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI
AVN
ARISTO
Share %
Antibiotic Market: Incepta & Opsonin have high
growth
10
22.29
7.47
6.77 6.43 6.16
5.20 5.11 5.09 4.75
3.47
6.99
23.97
12.99
8.85
12.67
1.27
17.67
9.73
6.19
4.45
SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI
AVN
ARISTO
Share % Growth %
Antibiotic Market: 4 companies in top 10 are loosing
share
11
22.29
7.47 6.77 6.43 6.16
5.20 5.11 5.09 4.75
3.47
-1.11
14.57
4.48
0.63
4.05
-6.47
8.72
1.39
-2.06
-3.34
SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI
AVN
ARISTO
Share % Share Growth %
• Cefuroxime Axetil Market
13
Cefuroxime Market: 78% mkt in 3 divisions:
90% in 4 divisions
Dhaka
37%
Chittagong
21%
Rajshahi
20%
Khulna
12%
Barisal
6%
Sylhet
4%
Share %
14
Cefuroxime: market growth is driven by North Bengal
Growth in DHK & CHT is lower than national growth (19%)
37.40
20.77 19.73
12.13
6.04
3.93
16.71
14.20
27.90
19.14
29.97
20.02
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Share % Growth %
15
Kilmax: DHK division doing wonderful!
Under-performing in North Bengal & Barisal
5.13
4.36
4.07
4.51
3.56
4.79
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS %
16
Kilmax: DHK having high MS, still growing
Growth improvement opportunity in CHT
5.13 4.36 4.07 4.51 3.56 4.79
37.67
-0.20
47.65
13.52
49.84
9.43
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS % Gr %
17
Furosef VS. Kilmax: High market share gap (13%) in
CHT, low gap in RAJ (7%)
17.19
17.81
11.66
15.53 15.49
17.55
5.13
4.36 4.07 4.51
3.56
4.79
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS %
FUROCEF-RTA KILMAX-ESF
18
Kilbac Vs. Kilmax: High market share gap in CHT
13.05
14.60
10.86 11.20 11.56
10.87
5.13
4.36 4.07 4.51
3.56
4.79
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS %
KILBAC-IAP KILMAX-ESF
19
Kilbac Vs. Kilmax: GAP Analysis
7.92
10.24
6.79 6.69
8.00
6.08
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
KIlbac VS. Kilmax
GAP
20
Top 5 District: Kilmax MS% high in Mymensingh
Low in Comilla
4.08
4.82
5.50
3.46
4.21
Dhaka Chittagong Mynensingh Comilla Khulna
Kilmax
Share %
21
Top 5 District: Kilmax growth % high in Mymensingh
Negative in Chittagong
9.96
17.12
29.06
20.87 18.91
28.29
-5.29
90.00
39.85 36.93
Dhaka Chittagong Mynensingh Comilla Khulna
Market Growth
Market Kilmax
• Clindamycin Market
23
Clindamycin Market: Dhaka and Rajshahi division
dominates the market
Dhaka
39%
Rajshahi
25%
Khulna
14%
Chittagong
14%
Barisal
5%
Sylhet
3%
Share %
24
39.39
24.75
14.36 13.85
4.40 3.25
45.87
53.83
29.83
11.19
41.71
23.91
Dhaka Rajshahi Khulna Chittagong Barisal Sylhet
Share % Growth %
Clindamycin Market: Very high growth for Dhaka,
Rajshahi & Barisal division
25
Incepta VS. Opsonin: Market share GAP is low (7%
GAP) in DHK; High in KHL (18%)
31.34
34.51
39.60
36.96
31.67 30.34
23.96 23.62
21.35
23.80
28.02
25.74
Dhaka Rajshahi Khulna Chittagong Barisal Sylhet
CLINDACIN-IAP CLINDAX-OPI
26
Incepta VS. Opsonin: Clindax growth is better than
Clindacin in all divisions
Major growth difference in Dhaka & Barisal division
11.66
25.44
6.68
-8.12
8.52
-4.89
60.12
37.57
10.61
3.00
40.43
23.78
Dhaka Rajshahi Khulna Chittagong Barisal Sylhet
CLINDACIN-IAP CLINDAX-OPI
• The Anti-ulcer Market
Anti-ulcer Market: 3 ESF brands in top 50 ;
QTR figure is encouraging
28
RK~MAT
06/2012
RK~YTD
06/2012
RK~QTR
06/2012
LOSECTIL 2 2 1
PEPTIL-H 21 28 26
ESORAL 29 21 17
• Omeprazole Market
30
Omeprazole Market: 60% mkt in 2 divisions:
90% in 4 divisions
Dhaka
34%
Chittagong
24%
Rajshahi
19%
Khulna
12%
Barisal
7%
Sylhet
4%
Share %
31
Losectil in Omeprazole Market: High MS in KHL
Whatever happened in BSL?
19.36 19.21 18.96
22.31
13.94
21.82
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Losectil
Share %
32
Losectil in Omeprazole Market: High Growth in KHL
Lower growth in DHK
19.36 19.21 18.96 22.31
13.94
21.82
22.09
37.14 28.15
100.21
40.31
49.52
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Losectil
Share % Growth %
33
Seclo Vs. Losectil: market share equally low in all
divisions
Still losing ground in DHK, RAJ, KHL, SYL
19.36 19.21 18.96
22.31
13.94
21.82
28.20
27.06 26.19 26.74
28.10
19.15
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS %
Losectil Seclo
34
Seclo Vs. Losectil: Low gap in KHL
Losectil beats Seclo in SYL!
8.84 7.85 7.23
4.43
14.16
-2.67
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Losectil Vs. Seclo
GAP
35
Losectil Share % in 5 Major District: High in CHT
Low in COM, MYM
20.74
23.48
13.92
17.28
19.67
Dhaka Chittagong Comilla Mynensingh Khulna
MS %
LOSECTIL
36
Seclo Vs. Losectil: 5 Major District
20.74
23.48
13.92
17.28
19.67
27.87 27.34 26.83
36.12
24.00
Dhaka Chittagong Comilla Mynensingh Khulna
MS %
LOSECTIL SECLO
37
GAP Analysis in District Level:
High gap in MYM & COM
7.13
3.86
12.91
18.84
4.33
Dhaka Chittagong Comilla Mynensingh Khulna
GAP
20.74
23.48
13.92
17.28
19.67
27.87 27.34 26.83
36.12
24.00
Dhaka Chittagong Comilla Mynensingh Khulna
MS %
LOSECTIL SECLO
• Esomeprazole Market
39
Esomeprazole: Share is good in DHK & BSL
Lot of works to be done in North Bengal
3.90
3.38
2.94
3.79 3.91
3.41
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Esoral
Share %
40
Esomeprazole Market Vs. Esoral Growth
51.67
38.72
79.46
61.60
73.74
55.42
199.39
154.03
218.22 208.34 206.15
161.73
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Growth %
Esomeprazole Esoral
41
Maxpro Vs. Esoral: Where is the biggest gap?
24.36 24.81
19.57
21.64
25.43
19.44
3.90 3.38 2.94 3.79 3.91 3.41
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
MS %
Maxpro Esoral
42
Maxpro Vs. Esoral: High GAP in CHT & BSL
20.46 21.43
16.63
17.85
21.52
16.03
Dhaka Chittagong Rajshahi Khulna Barisal Sylhet
Maxpro Vs. Esoral
GAP
43
Esoral in Top 5 District
Dhaka Chittagong Comilla Khulna Mynensingh
1 MAXPRO RTA
MAXPRO
RTA
MAXPRO
RTA MAXPRO RTA
MAXPRO
RTA
2 SERGEL HT3 SERGEL HT3
SERGEL
HT3 SERGEL HT3
NEXUM
SQA
3 NEXUM SQA
SOMPRAZ
SPI
NEXUM
SQA ESONIX IAP
SERGEL
HT3
4 ESONIX IAP ESONIX IAP
EXIUM
RD7 MAXIMA ACM
EXIUM
RD7
5 EXIUM RD7 NEXUM SQA ESONIX IAP NEXUM SQA ESONIX IAP
6 ESOTID OPI EXIUM RD7
SOMPRAZ
SPI EXIUM RD7
ESORAL
ESF
7 ESORAL ESF ESORAL ESF
ESOTID
OPI PROGESIC IAP
ESOTID
OPI
8 PROGESIC IAP ESOTID OPI NESO ATP SOMPRAZ SPI
PROGUT
PPH
9 NEPTOR SDZ ESOLOK IBN
ESORAL
ESF ESOTID OPI
SOMPRAZ
SPI
10 NESO ATP
PROGUT
PPH
MAXIMA
ACM NESO ATP
OPTON
BXM
?
• The Anti-ulcer Market:
• Promotional Preference
45
CHT: Important for Ranitidine market
24.26 23.71 23.11 22.72
27.96
Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine
Chittagong
46
RAJ: Important for Pantoprazole
18.55
19.88
18.67
17.04
15.76
Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine
Rajshahi
47
DHK: Important for Rabeprazole & Ranitidine
34.18
34.77
34.97
36.47
36.11
Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine
Dhaka
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Bangladesh pharma market dynamics 2 q 2012

  • 2. • Confidentiality Statement This presentation is solely for the use of IMS clients. No part of it may be circulated, quoted or reproduced for distribution outside of the client organization without prior written approval of IMS Health
  • 4. Bangladesh pharma market: Eskayef is the number 6 company with 4.74% market share 4 18.42 9.52 8.88 5.33 4.93 4.74 4.31 4.12 4.03 3.73 SQUARE INCEPTA BEXIMCO OPSONIN RENATA ESKAYEF A.C.I. ACME ARISTO DRUG INTL Share %
  • 5. Evolution of market share: Top 10 Companies Recent data indicates good performance of Incepta, Opsonin, Renata & DI 5 MAT ~ 06/2012 YTD ~ 06/2012 QTR ~ 06/2012 SQUARE 18.42 18.17 17.13 INCEPTA 9.52 9.70 9.78 BEXIMCO 8.88 8.75 8.49 OPSONIN 5.33 5.44 5.47 RENATA 4.93 5.02 5.14 ESKAYEF 4.74 4.74 4.71 A.C.I. 4.31 4.16 4.22 ACME 4.12 4.20 4.07 ARISTO 4.03 4.08 4.07 DRUG INTL 3.73 3.83 3.97
  • 7. Antibiotic Market: Top 12 Molecules represents 90% of the 1700 Crore Taka Market 7 17.63 15.79 11.85 10.96 7.68 6.59 6.55 5.47 2.68 1.98 1.81 1.32 Share %
  • 8. Clindamycin (39% gr) is the highest growing molecule, followed by Cefuroxime (19% gr) 8 38.80 19.39 18.12 17.76 15.73 6.65 0.65 0.33 -4.11 -4.32 -5.57 -10.29 Growth %
  • 9. Top Companies in Antibiotic Market: ESK number 8 Renta 3, ACI 5, Sanofi 9 9 22.29 7.47 6.77 6.43 6.16 5.20 5.11 5.09 4.75 3.47 SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI AVN ARISTO Share %
  • 10. Antibiotic Market: Incepta & Opsonin have high growth 10 22.29 7.47 6.77 6.43 6.16 5.20 5.11 5.09 4.75 3.47 6.99 23.97 12.99 8.85 12.67 1.27 17.67 9.73 6.19 4.45 SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI AVN ARISTO Share % Growth %
  • 11. Antibiotic Market: 4 companies in top 10 are loosing share 11 22.29 7.47 6.77 6.43 6.16 5.20 5.11 5.09 4.75 3.47 -1.11 14.57 4.48 0.63 4.05 -6.47 8.72 1.39 -2.06 -3.34 SQUARE INCEPTA RENATA BEXIMCO A.C.I. ACME OPSONIN ESKAYEF SANOFI AVN ARISTO Share % Share Growth %
  • 13. 13 Cefuroxime Market: 78% mkt in 3 divisions: 90% in 4 divisions Dhaka 37% Chittagong 21% Rajshahi 20% Khulna 12% Barisal 6% Sylhet 4% Share %
  • 14. 14 Cefuroxime: market growth is driven by North Bengal Growth in DHK & CHT is lower than national growth (19%) 37.40 20.77 19.73 12.13 6.04 3.93 16.71 14.20 27.90 19.14 29.97 20.02 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Share % Growth %
  • 15. 15 Kilmax: DHK division doing wonderful! Under-performing in North Bengal & Barisal 5.13 4.36 4.07 4.51 3.56 4.79 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS %
  • 16. 16 Kilmax: DHK having high MS, still growing Growth improvement opportunity in CHT 5.13 4.36 4.07 4.51 3.56 4.79 37.67 -0.20 47.65 13.52 49.84 9.43 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS % Gr %
  • 17. 17 Furosef VS. Kilmax: High market share gap (13%) in CHT, low gap in RAJ (7%) 17.19 17.81 11.66 15.53 15.49 17.55 5.13 4.36 4.07 4.51 3.56 4.79 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS % FUROCEF-RTA KILMAX-ESF
  • 18. 18 Kilbac Vs. Kilmax: High market share gap in CHT 13.05 14.60 10.86 11.20 11.56 10.87 5.13 4.36 4.07 4.51 3.56 4.79 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS % KILBAC-IAP KILMAX-ESF
  • 19. 19 Kilbac Vs. Kilmax: GAP Analysis 7.92 10.24 6.79 6.69 8.00 6.08 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet KIlbac VS. Kilmax GAP
  • 20. 20 Top 5 District: Kilmax MS% high in Mymensingh Low in Comilla 4.08 4.82 5.50 3.46 4.21 Dhaka Chittagong Mynensingh Comilla Khulna Kilmax Share %
  • 21. 21 Top 5 District: Kilmax growth % high in Mymensingh Negative in Chittagong 9.96 17.12 29.06 20.87 18.91 28.29 -5.29 90.00 39.85 36.93 Dhaka Chittagong Mynensingh Comilla Khulna Market Growth Market Kilmax
  • 23. 23 Clindamycin Market: Dhaka and Rajshahi division dominates the market Dhaka 39% Rajshahi 25% Khulna 14% Chittagong 14% Barisal 5% Sylhet 3% Share %
  • 24. 24 39.39 24.75 14.36 13.85 4.40 3.25 45.87 53.83 29.83 11.19 41.71 23.91 Dhaka Rajshahi Khulna Chittagong Barisal Sylhet Share % Growth % Clindamycin Market: Very high growth for Dhaka, Rajshahi & Barisal division
  • 25. 25 Incepta VS. Opsonin: Market share GAP is low (7% GAP) in DHK; High in KHL (18%) 31.34 34.51 39.60 36.96 31.67 30.34 23.96 23.62 21.35 23.80 28.02 25.74 Dhaka Rajshahi Khulna Chittagong Barisal Sylhet CLINDACIN-IAP CLINDAX-OPI
  • 26. 26 Incepta VS. Opsonin: Clindax growth is better than Clindacin in all divisions Major growth difference in Dhaka & Barisal division 11.66 25.44 6.68 -8.12 8.52 -4.89 60.12 37.57 10.61 3.00 40.43 23.78 Dhaka Rajshahi Khulna Chittagong Barisal Sylhet CLINDACIN-IAP CLINDAX-OPI
  • 28. Anti-ulcer Market: 3 ESF brands in top 50 ; QTR figure is encouraging 28 RK~MAT 06/2012 RK~YTD 06/2012 RK~QTR 06/2012 LOSECTIL 2 2 1 PEPTIL-H 21 28 26 ESORAL 29 21 17
  • 30. 30 Omeprazole Market: 60% mkt in 2 divisions: 90% in 4 divisions Dhaka 34% Chittagong 24% Rajshahi 19% Khulna 12% Barisal 7% Sylhet 4% Share %
  • 31. 31 Losectil in Omeprazole Market: High MS in KHL Whatever happened in BSL? 19.36 19.21 18.96 22.31 13.94 21.82 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Losectil Share %
  • 32. 32 Losectil in Omeprazole Market: High Growth in KHL Lower growth in DHK 19.36 19.21 18.96 22.31 13.94 21.82 22.09 37.14 28.15 100.21 40.31 49.52 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Losectil Share % Growth %
  • 33. 33 Seclo Vs. Losectil: market share equally low in all divisions Still losing ground in DHK, RAJ, KHL, SYL 19.36 19.21 18.96 22.31 13.94 21.82 28.20 27.06 26.19 26.74 28.10 19.15 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS % Losectil Seclo
  • 34. 34 Seclo Vs. Losectil: Low gap in KHL Losectil beats Seclo in SYL! 8.84 7.85 7.23 4.43 14.16 -2.67 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Losectil Vs. Seclo GAP
  • 35. 35 Losectil Share % in 5 Major District: High in CHT Low in COM, MYM 20.74 23.48 13.92 17.28 19.67 Dhaka Chittagong Comilla Mynensingh Khulna MS % LOSECTIL
  • 36. 36 Seclo Vs. Losectil: 5 Major District 20.74 23.48 13.92 17.28 19.67 27.87 27.34 26.83 36.12 24.00 Dhaka Chittagong Comilla Mynensingh Khulna MS % LOSECTIL SECLO
  • 37. 37 GAP Analysis in District Level: High gap in MYM & COM 7.13 3.86 12.91 18.84 4.33 Dhaka Chittagong Comilla Mynensingh Khulna GAP 20.74 23.48 13.92 17.28 19.67 27.87 27.34 26.83 36.12 24.00 Dhaka Chittagong Comilla Mynensingh Khulna MS % LOSECTIL SECLO
  • 39. 39 Esomeprazole: Share is good in DHK & BSL Lot of works to be done in North Bengal 3.90 3.38 2.94 3.79 3.91 3.41 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Esoral Share %
  • 40. 40 Esomeprazole Market Vs. Esoral Growth 51.67 38.72 79.46 61.60 73.74 55.42 199.39 154.03 218.22 208.34 206.15 161.73 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Growth % Esomeprazole Esoral
  • 41. 41 Maxpro Vs. Esoral: Where is the biggest gap? 24.36 24.81 19.57 21.64 25.43 19.44 3.90 3.38 2.94 3.79 3.91 3.41 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet MS % Maxpro Esoral
  • 42. 42 Maxpro Vs. Esoral: High GAP in CHT & BSL 20.46 21.43 16.63 17.85 21.52 16.03 Dhaka Chittagong Rajshahi Khulna Barisal Sylhet Maxpro Vs. Esoral GAP
  • 43. 43 Esoral in Top 5 District Dhaka Chittagong Comilla Khulna Mynensingh 1 MAXPRO RTA MAXPRO RTA MAXPRO RTA MAXPRO RTA MAXPRO RTA 2 SERGEL HT3 SERGEL HT3 SERGEL HT3 SERGEL HT3 NEXUM SQA 3 NEXUM SQA SOMPRAZ SPI NEXUM SQA ESONIX IAP SERGEL HT3 4 ESONIX IAP ESONIX IAP EXIUM RD7 MAXIMA ACM EXIUM RD7 5 EXIUM RD7 NEXUM SQA ESONIX IAP NEXUM SQA ESONIX IAP 6 ESOTID OPI EXIUM RD7 SOMPRAZ SPI EXIUM RD7 ESORAL ESF 7 ESORAL ESF ESORAL ESF ESOTID OPI PROGESIC IAP ESOTID OPI 8 PROGESIC IAP ESOTID OPI NESO ATP SOMPRAZ SPI PROGUT PPH 9 NEPTOR SDZ ESOLOK IBN ESORAL ESF ESOTID OPI SOMPRAZ SPI 10 NESO ATP PROGUT PPH MAXIMA ACM NESO ATP OPTON BXM ?
  • 44. • The Anti-ulcer Market: • Promotional Preference
  • 45. 45 CHT: Important for Ranitidine market 24.26 23.71 23.11 22.72 27.96 Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine Chittagong
  • 46. 46 RAJ: Important for Pantoprazole 18.55 19.88 18.67 17.04 15.76 Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine Rajshahi
  • 47. 47 DHK: Important for Rabeprazole & Ranitidine 34.18 34.77 34.97 36.47 36.11 Omeprazole Pantoprazole Esomeprazole Rabeprazole Ranitidine Dhaka